REVIEW OF
Goodbye to high BP and obesity -Health/Sci-The Times of India
THE TIMES OF INDIA
article by Rupali Mukherjee rupali.mukherjee@timesgroup.com
06/15/08 06:42:47 PM
Rupali Mukherjee has informed about giving patients FIVE different medicines in one attractive packing. WRAPPER KA JAMANA
Physicians prefer to give medicines selectively and separately.
Reasons:
to know which medicine best suits that particular patient and the dose that is best tolerated.
This allows the Physician to give tailor made treatment according to the specific requirement of the patient. People are different, aren't they?
Combo Pack containing combination of all medicines in one capsule has been looked down upon by practicing Physicians, especially the intensivist (Intensive Care Unit - ICU - Specialists***reference) and the super specialists. It becomes difficult to monitor critical parameters of patient.
This idea of selling different medicines as a bundle (pun intended) used rampantly even now while giving antibiotics has been labeled "Shot Gun Therapy". The implied meaning is, "If not this, the other drug may work". This has caused havoc in antibiotic therapy by bringing out drug resistant strains of micro organisms.
We look forward to inspiring articles emphasizing the value of the BEST MEDICAL INSURANCE POLICY AVAILABLE TODAY, namely "PHYSICAL EXERCISE" as a part of life style modification.
***REFERENCE
Ethics Committee, Society of Critical Care Medicine. "Consensus Statement of the SCCM Ethics Committee Regarding Futile and Other Possibly Inadvisable Treatments." Critical Care Medicine 25 (May 1997): 887-891.
REVIEW BY Dr. Ashok Koparday
http://mydoctortells.blogspot.com
OVER
THE TIMES OF INDIA
Article Verbatim titled
15 Jun 2008, 0502 hrs IST, Rupali Mukherjee,TNN
THE TIMES OF INDIA
article by Rupali Mukherjee rupali.mukherjee@timesgroup.com
It is many medicines in one bag.
It contains not one but 5 different medicines so if something goes wrong you do not know which of the medicine is the culprit.
There are three blood
pressure lowering agents, an antiplatelet drug, a beta blocker, an ACE
inhibitor, a diuretic and a statin.
06/15/08 06:42:47 PM
Rupali Mukherjee has informed about giving patients FIVE different medicines in one attractive packing. WRAPPER KA JAMANA
Physicians prefer to give medicines selectively and separately.
Reasons:
[1]
to know which medicine best suits that particular patient and the dose that is best tolerated.
This allows the Physician to give tailor made treatment according to the specific requirement of the patient. People are different, aren't they?
[2]
Combo Pack containing combination of all medicines in one capsule has been looked down upon by practicing Physicians, especially the intensivist (Intensive Care Unit - ICU - Specialists***reference) and the super specialists. It becomes difficult to monitor critical parameters of patient.
[3]
This idea of selling different medicines as a bundle (pun intended) used rampantly even now while giving antibiotics has been labeled "Shot Gun Therapy". The implied meaning is, "If not this, the other drug may work". This has caused havoc in antibiotic therapy by bringing out drug resistant strains of micro organisms.
We look forward to inspiring articles emphasizing the value of the BEST MEDICAL INSURANCE POLICY AVAILABLE TODAY, namely "PHYSICAL EXERCISE" as a part of life style modification.
***REFERENCE
Ethics Committee, Society of Critical Care Medicine. "Consensus Statement of the SCCM Ethics Committee Regarding Futile and Other Possibly Inadvisable Treatments." Critical Care Medicine 25 (May 1997): 887-891.
REVIEW BY Dr. Ashok Koparday
http://mydoctortells.blogspot.com
OVER
THE TIMES OF INDIA
Article Verbatim titled
Goodbye to high BP and obesity
15 Jun 2008, 0502 hrs IST, Rupali Mukherjee,TNN
NEW DELHI: Can a single pill treat problems of high blood pressure, reduce cholesterol level and act as a blood thinner? Seems like this may be possible soon. In one of the largest clinical trials being conducted for the first time, the impact of the 'wonder drug' is being assessed across 20 cities in India.
The trials of the drug 'polypack' manufactured by Cadila Pharmaceuticals are being conducted on 2,000 subjects, between the age of 45 and 80 years, who have any one of the risk factors - age, obesity, high blood pressure, high cholesterol or high blood sugar.
The 'polypack' contains a combination of five drugs in eight different formulations (three blood pressure lowering agents, an antiplatelet drug, a beta blocker, an ACE inhibitor, a diuretic and a statin) for treating cardio-vascular conditions such as reducing blood pressure and lowering cholesterol levels.
Simply put, the polypack includes blood pressure lowering combinations, aspirin (blood thinner) and a statin, which is a cholesterol lowering agent.
The trials are being conducted by St John Research Institute, Bangalore and Canada-based Population Health Research Institute.
"We need to assess the impact (efficacy) of the different combinations on an individual who has cardio-vascular risk factors, and also the safety of these drugs taken together. The side-effects of the five medicines will also be studied," says Dr Rajeev Gupta of Fortis Hospital, Jaipur who is involved in the study.
The subjects will be given the combination drug for three months and a follow up will be done in the fourth month. The trials will be completed by July and findings put together by end of the year.
The second phase of trials will assess whether heart attacks and strokes can be prevented with the combination drug, Gupta added.
Cardiovascular diseases are major causes of mortality in the Indian subcontinent, causing over 30% of deaths. It has been predicted that these diseases will increase rapidly and India will contribute to over half the cases of heart diseases in the world within the next 15 years.
Coronary heart disease and stroke have increased in both urban and rural areas. The sharp rise in cardiovascular problems including heart disease and stokes is attributed to increasing number of smokers, obesity with high waist to hip ratio, high blood pressure, high cholesterol, stress and sedentary lifestyle.
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