The story behind the search that led to the use of this useful medicine Paracetamol is as fascinating as the story of Albert Einstein or Sir Isaac Newton. However, you do not know about it. How will you know unless you read this.
Interesting Search
for a better Pain Relieving Medicine
In 1963, paracetamol was added to the British Pharmacopoeia, and has gained popularity since then as an analgesic agent with few side-effects and little interaction with other pharmaceutical agents.
In 1946, the Institute for the Study of Analgesic and Sedative Drugs awarded a grant to the New York City Department of Health to study the problems associated with analgesic agents.
In 1948, Brodie and Axelrod linked the use of acetanilide with methemoglobinemia and determined that the analgesic effect of acetanilide was due to its active metabolite paracetamol. They advocated the use of paracetamol, since it did not have the toxic effects of acetanilide.
The product went on sale in the United States in 1955 under the brand name Tylenol.
In 1956, 500 mg tablets of paracetamol went on sale in the United Kingdom under the trade name Panadol
Produced by Frederick Stearns & Co, a subsidiary of Sterling Drug Inc.
Aspirin was derived from the bark of the cinchona tree. When the cinchona tree became scarce in the 1880s, people began to look for alternatives. Two alternative anti fever (antipyretic) agents were developed in the 1880s: acetanilide in 1886 and phenacetin in 1887.
In ancient and medieval times, known (anti fever)antipyretic agents were compounds contained in white willow bark (a family of chemicals known as salicins, which led to the development of aspirin), and compounds contained in cinchona bark. Cinchona bark was also used to create the anti-malaria drug quinine.here is the rest of it.
Interesting Search
for a better Pain Relieving Medicine
In 1963, paracetamol was added to the British Pharmacopoeia, and has gained popularity since then as an analgesic agent with few side-effects and little interaction with other pharmaceutical agents.
In 1946, the Institute for the Study of Analgesic and Sedative Drugs awarded a grant to the New York City Department of Health to study the problems associated with analgesic agents.
In 1948, Brodie and Axelrod linked the use of acetanilide with methemoglobinemia and determined that the analgesic effect of acetanilide was due to its active metabolite paracetamol. They advocated the use of paracetamol, since it did not have the toxic effects of acetanilide.
The product went on sale in the United States in 1955 under the brand name Tylenol.
In 1956, 500 mg tablets of paracetamol went on sale in the United Kingdom under the trade name Panadol
Produced by Frederick Stearns & Co, a subsidiary of Sterling Drug Inc.
Aspirin was derived from the bark of the cinchona tree. When the cinchona tree became scarce in the 1880s, people began to look for alternatives. Two alternative anti fever (antipyretic) agents were developed in the 1880s: acetanilide in 1886 and phenacetin in 1887.
In ancient and medieval times, known (anti fever)antipyretic agents were compounds contained in white willow bark (a family of chemicals known as salicins, which led to the development of aspirin), and compounds contained in cinchona bark. Cinchona bark was also used to create the anti-malaria drug quinine.here is the rest of it.
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